Prednisone can be used by people who experience the unpleasant and dangerous symptoms of low corticosteroid levels. It works by replacing steroids that are not produced in sufficient amounts by the body and can change the way the immune system works. If you know you are about to experience stress (in case of a planned surgery, asthma attack or infection) your dose may need to be changed by the doctor that prescribed prednisone. Patients diagnosed with a mental illness, tuberculosis, high blood pressure, liver, kidney, intestinal, heart, or thyroid disease, eye infection, threadworms, seizures, myasthenia gravis, osteoporosis, ulcers, or diabetes must discuss all the risk and benefits of their treatment with prednisone. They may be able to take this medicine only having some tests done or their dose will be decreased to make sure they are benefitting from the treatment. If you are taking any of the following medicines make sure your health care provider is aware of this fact: aspirin, anticoagulants, hormonal contraceptives, HIV protease inhibitors, diuretics, medications for diabetes, fluoxetine, fluvoxamine, amiodarone, carbamazepine, sertraline, delavirdine, dexamethasone, cyclosporine, clarithromycin, diltiazem, troleandomycin, rifampin, verapamil, lovastatin, antifungals, or cimetidine. If you are not sure whether the drug you are currently taking belongs to any of these groups, consult your pharmacist or read the label carefully.